How cells take out the trash: The 'phospho-kiss of death' deciphered
- Fri 07 Oct 2016 12:46:PM
Cells never forget to take out the trash. It has long been known that cells tag proteins for degradation by labeling them with ubiquitin, a signal described as “the molecular kiss of death”. Now a research group has identified an analogous system in gram-positive bacteria, where the role of a degradation tag is fulfilled by a little known post-translational modification: arginine phosphorylation. The discovery opens new avenues for designing antibacterial therapies.
Source: How cells take out the trash: The 'phospho-kiss of death' deciphered
Source: How cells take out the trash: The 'phospho-kiss of death' deciphered